Comparative study of transient elastography versus real-time tissue elastography for assessment of liver fibrosis in patients with chronic liver disease.
- Author:
Jian ZHENG
1
;
Lixin YANG
;
Tao WU
;
Jie ZENG
;
Zeping HUANG
;
Bowen ZHENG
;
Hongjun ZHANG
;
Rongqin ZHENG
Author Information
- Publication Type:Journal Article
- MeSH: Autoimmune Diseases; Elasticity Imaging Techniques; Hepatitis B, Chronic; diagnostic imaging; Hepatitis C, Chronic; diagnostic imaging; Humans; Liver Cirrhosis, Biliary; diagnostic imaging; ROC Curve
- From: Chinese Journal of Hepatology 2014;22(10):731-734
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo compare the abilities of transient elastography (TE) versus real-time tissue elastography (RTE) for assessing liver fibrosis in patients with chronic liver disease.
METHODSNinetytwo patients with chronic liver disease were enrolled in the study, and included 77 cases of chronic hepatitis B, 4 cases of chronic hepatitis C, 4 cases of autoimmune liver disease, 2 cases of primary biliary cirrhosis, I case of abnormal bile duct development, and 4 cases of unknown etiology.All patients were assessed by both TE and RTE in a single day.The correlation coefficient of liver fibrosis level and the receiver operating characteristic (ROC) curve of S more than 2 and =4 of TE and RTE were determined.The values were compared using findings fiom pathological analysis as reference.
RESULTSThe correlation coefficient of liver fibrosis level was significantly higher for TE (r =0.755, 95% CI:0.651-0.831, P =0.000) than for RTE (r=0.481, 95% CI:0.306-0.624, P =0.000) (Z=3.07, P =0.002).The areas under the ROC curves for S more than 2 and =4 were 0.903 and 0.740 for TE and 0.915 and 0.786 for RTE, respectively, indicating that the performance of TE was superior to that of RTE.
CONCLUSIONTE was superior to RTE for assessment of liver fibrosis.
