Research advances on mechanisms of chemoresistance in acute myeloid leukemia.
- Author:
Chun-mei YANG
1
;
Wen-bin QIAN
Author Information
1. The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
- Publication Type:Journal Article
- MeSH:
Drug Resistance, Neoplasm;
physiology;
Humans;
Leukemia, Myeloid, Acute;
drug therapy;
physiopathology
- From:
Journal of Zhejiang University. Medical sciences
2012;41(5):576-580
- CountryChina
- Language:Chinese
-
Abstract:
Acute myeloid leukemia (AML) is a common type of hematopoietic malignancies seriously threatening human life. Resistance to chemotherapy is one of the main reasons for recurrence and refractoriness of acute myeloid leukemia. The mechanisms of chemoresistance are complex. This article reviews the mechanisms of chemoresistance in acute myeloid leukemia,the current research advances and the possible approach for reverse of drug resistance.
