Analysis of recurrence and prognosis after surgical resection for anorectal melanoma.
- Author:
Dong-Bing ZHAO
1
;
Yong-Kai WU
;
Yong-Fu SHAO
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Aged, 80 and over; Female; Humans; Lymphatic Metastasis; Male; Melanoma; pathology; surgery; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Rectal Neoplasms; pathology; surgery; Retrospective Studies; Survival Rate
- From: Chinese Journal of Gastrointestinal Surgery 2007;10(6):540-542
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the clinicopathologic factors related with recurrence and prognosis after surgical resection for anorectal melanoma.
METHODSThe clinicopathologic factors related to recurrence and prognosis of 50 patients with anorectal melanoma after surgical resection were retrospectively analyzed using univariate and multivariate methods.
RESULTSForty-seven patients underwent radical operation, including 31 abdominoperineal resection (APR) and 16 sphincter preserving operation. The local recurrence rates were 16.1%(5/31) and 68.8%(11/16) respectively. chi(2) analysis revealed that operation pattern was associated with local recurrence rate. The 5-year survival rate was 18.2%. Univariate analysis revealed that single tumor, intramural infiltration and operation pattern were related with prognosis. Multivariate analysis revealed that intramural infiltration was the most important prognostic factor for anorectal melanoma.
CONCLUSIONSThe prognosis of anorectal melanoma is poor. Early diagnosis and treatment are important for the improving of curative effect.
