Culture-independent digging of cellulases and genes from natural environments.
- Author:
Yongtao ZHU
1
;
Weifeng LIU
;
Lushan WANG
;
Guanjun CHEN
Author Information
1. State Key Laboratory of Microbial Technology, Shandong University, Jinan 250100, China.
- Publication Type:Journal Article
- MeSH:
Bacteria;
enzymology;
genetics;
Cellulases;
genetics;
metabolism;
Cellulose;
metabolism;
Cloning, Molecular;
Environmental Microbiology;
Genome, Bacterial;
Metagenomics
- From:
Chinese Journal of Biotechnology
2009;25(12):1838-1843
- CountryChina
- Language:Chinese
-
Abstract:
There is a great diversity for cellulolytic microbes in nature and the strategies they use to digest cellulose. In addition to the cultured cellulolytic microbes, there are still a great number of microbes being not readily culturable in natural environments, which may represent great potential for identifying novel cellulases and their encoding genes. The rise of metagenomics and metaproteomics provides essential technologic tools to dig up these resources and significant progress has been made so far. This review gives an insight into some relative results that have arisen from the meta-genomic or proteomic analysis of definitive uncultured microbe communities. Their potential role in elucidating the process and mechanisms of cellulose degradation in natural environment from the point of "community system microbiology" is also discussed.
