Risk factors for cerebral microbleeds.
- Author:
Yi-ka FANG
1
;
Su-yue PAN
Author Information
- Publication Type:Journal Article
- MeSH: Cerebral Hemorrhage; epidemiology; etiology; pathology; China; epidemiology; Diabetes Complications; Female; Humans; Hypertension; complications; Magnetic Resonance Imaging; methods; Male; Middle Aged; Risk Factors
- From: Journal of Southern Medical University 2010;30(6):1425-1427
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo analyze the risk factors of cerebral microbleeds (CMBs).
METHODSA total of 113 patients with cerebrovascular diseases underwent examinations of magnetic resonance imaging (MRI) of the brain (including T1WI, T2WI, FLAIR, and SWI) and blood biochemical tests, and the brain regions, number and grades of the CMBs were analyzed. The association between CMBs and the cardiovascular risk factors were analyzed.
RESULTSA The occurrence and grade of CMBs were associated with the patients' age, hypertension, diabetes, lacunar infarction, diastolic blood pressure, systolic blood pressure and high-density lipoprotein (HDL) levels (P<0.05). CMB occurrence was significantly associated with diabetes, hypertension, and lacunar infarction (P<0.05), and its incidence varied significantly between different brain regions (P<0.05).
CONCLUSIONAge, hypertension, diabetes, lacunar infarction, diastolic blood pressure, systolic blood pressure, and HDL are all risk factors for CMBs, among which diabetes, hypertension, and lacunar infarction are significant risk factors. CMBs occurs most frequently in the cortex and subcortical region, followed by the basal ganglia, thalamus, and the cerebellum, and most unlikely in the brainstem.
