Subcutaneous implantation of embryonic skin cells to construct a model of hair development in nude mice.
- Author:
Ming-juan CHEN
1
;
Zhi-qi HU
;
Ting TAN
;
Xi-jin SUN
;
Yong MIAO
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Cell Transplantation; Cells, Cultured; Dermis; cytology; transplantation; Embryo, Mammalian; Epidermis; cytology; transplantation; Hair; growth & development; Mice; Mice, Inbred C57BL; Mice, Nude; Models, Animal; Skin; cytology
- From: Journal of Southern Medical University 2009;29(10):2024-2026
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo observe the hair development after subcutaneous implantation of embryonic skin cells in nude mice, and construct a model of hair development.
METHODSDermal and epidermal cells isolated from embryonic mouse skin were mixed at a given ratio and injected subcutaneously in nude mice, and hair formation after the implantation was observed under a microscope.
RESULTSFormation of the hair follicles and fibers under the skin of the recipient nude mice and emergence of the hair shaft were observed microscopically.
CONCLUSIONEmbryonic skin cells be used to construct a complete model of hair development after implantation in vivo.
