Sesquiterpenes from Artabotrys hongkongensis.
10.19540/j.cnki.cjcmm.2017.0124
- Author:
Shui-Ling WU
1
;
Yan-Ping LIU
1
;
Guang-Ying CHEN
1
;
Chang-Ri HAN
1
;
Xiao-Ping SONG
1
;
Xia ZHONG
2
;
Yan-Hui FU
1
Author Information
1. Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, Hainan Normal University, Haikou 571158, China.
2. College of Pharmacy, Hainan Medical University, Haikou 571199, China.
- Publication Type:Journal Article
- Keywords:
Annonaceae;
Artabotrys;
Artabotrys hongkongensis;
chemical constituents;
sesquiterpenes
- From:
China Journal of Chinese Materia Medica
2017;42(16):3146-3151
- CountryChina
- Language:Chinese
-
Abstract:
The chemical consituents from Artabotrys hongkongensis were separated and purified by column chromatographies with silica gel, Sephadex LH-20, ODS and RP-HPLC. The structures of the isolated compounds were identified on the basis of physicochemical properties and spectroscopic analysis, as well as comparisons with the data reported in the literature. As a result, 16 sesquiterpenes were isolated and elucidated as blumenol A (1), 4, 5-dihydroblumenol A (2), (6R, 9S)-3-oxo-a-ionol (3), 3-hydroxy-β-ionone (4), dehydrovomifoliol (5), (3R, 6R, 7E) -3-hydroxy-4, 7-megastigmadien-9-one (6), sarmentol F (7), 10-oxo-isodauc-3-en-15-oic acid (8), fukinone (9), petasitolone (10), β-eudesmol (11), trans-3β-(1-hydroxy-1-methylethyl)- 8aβ-methyl-5-methylenedecalin-2-one (12), 10-hydroxyaristolan-9-one (13), aristol-8-en-1-one (14), aristolan-9-en-1-one (15), and aristolan-1, 9-diene (16). This is the first study on the chemical consituents of A. hongkongensis, and all compounds were isolated from the genus Artabotrys for the first time.