A new naphthalene derivative from Aloe vera and its antibacterial activity.
- Author:
Wei-Song KONG
1
;
Jing LI
1
;
Xin LIU
1
;
Qi-Li MI
1
;
Jian-Hua CHEN
1
;
Xue-Mei LI
1
;
Guang-Yu YANG
1
;
Qiu-Fen HU
1
;
Tao LI
2
;
Ye-Kun YANG
1
Author Information
- Publication Type:Journal Article
- Keywords: Aloe vera; antibacterial activity; naphthalene derivative
- From: China Journal of Chinese Materia Medica 2017;42(19):3761-3763
- CountryChina
- Language:Chinese
- Abstract: A new naphthalene derivative has been isolated from Aloe vera by using various chromatographic techniques, including silica gel, sephadex, MCI-gel resin, and RP-HPLC. The new compound was determined as 3-hydroxy-1-(1,7-dihydroxy-3,6-dimethoxynaphthalen-2-yl)propan-1-one (1). In the biological activity assay, compound 1 disglayed prominent antibacterial activity with a MIC90 value of (48±4) mg•L⁻¹ for methicillin resistant Staphylococcus aureus (MRSA) strain which was stronger than that of the positive control levofloxacin with a MIC90 value (58±5) mg•L⁻¹.
