Application progress of proteomic in pharmacological study of Chinese medicinal formulae.
10.19540/j.cnki.cjcmm.20170907.005
- Author:
Yu-Qian LIU
1
;
Shu-Yu ZHAN
1
;
Yu-Er RUAN
1
;
Zhi-Yan ZUO
1
;
Xiao-Ming JI
1
;
Shuai-Jie WANG
1
;
Bao-Yue DING
1
Author Information
1. Medical College, Jiaxing University, Jiaxing 314001, China.
- Publication Type:Journal Article
- Keywords:
Chinese medicinal formulae;
pharmacological study;
proteomic
- From:
China Journal of Chinese Materia Medica
2017;42(20):3873-3879
- CountryChina
- Language:Chinese
-
Abstract:
Chinese medicinal formulae are the important means of clinical treatment in traditional Chinese medicine. It is urgent to use modern advanced scientific and technological means to reveal the complicated mechanism of Chinese medicinal formulae because they have the function characteristics of multiple components, multiple targets and integrated regulation. The systematic and comprehensive research model of proteomic is in line with the function characteristics of Chinese medicinal formulae, and proteomic has been widely used in the study of pharmacological mechanism of Chinese medicinal formulae. The recent applications of proteomic in pharmacological study of Chinese medicinal formulae in anti-cardiovascular and cerebrovascular diseases, anti-liver disease, antidiabetic, anticancer, anti-rheumatoid arthritis and other diseases were reviewed in this paper, and then the future development direction of proteomic in pharmacological study of Chinese medicinal formulae was put forward. This review is to provide the ideas and method for proteomic research on function mechanism of Chinese medicinal formulae.
