Systematic evaluation for safety of traditional Chinese medicine Areca catechu and its preparations.
10.19540/j.cnki.cjcmm.20170919.014
- Author:
Lu SUN
1
;
Hai-Bo SONG
2
;
Li ZHANG
1
;
Ju-Kai HUANG
1
;
Jing-Xia WANG
3
;
Xiao-Hui YANG
1
;
Gui-Bo SUN
4
;
Xue-Min GAO
3
;
Xiao-Bo SUN
4
Author Information
1. Dongfang Hospital Affiliated to Beijing University of Chinese Medicine, Beijing 100078, China.
2. Center for Drug Reevaluation, China Food and Drug Administration, Beijing 100045, China.
3. Beijing University of Chinese Medicine, Beijing 100029, China.
4. Institute of Medicinal Plants, Chinese Academy of Medical Sciences, Beijing 100193, China.
- Publication Type:Journal Article
- Keywords:
Areca catechu;
adverse reaction;
risk control;
safety evaluation
- From:
China Journal of Chinese Materia Medica
2017;42(21):4067-4073
- CountryChina
- Language:Chinese
-
Abstract:
The authors systemically evaluated and analyzed the safety of Areca catechu from domestic and foreign literatures about the herbal origin, toxicity recorded in ancient/current documents, safety case reports of clinical A. catechu, experimental studies on toxicity in recent years, and differences of safety risk between edible and medicinal A. catechu. Subsequently, they proposed a preliminary summary about the clinical characteristics and potential risk factors of safety related cases of A. catechu and its preparations. According to the authors, although clinical adverse events of A. catechu were fewer and controllable, clinicians shall stillstrictly standardize its application, and rationally combine it with other herbs, while strengthening fundamental and clinical studies related to safety, so as to give better guidance to safety application of A. catechu in clinic.
