Evaluation of methods of quantifying.
- Author:
Hau Duc Tran
- Publication Type:Journal Article
- Keywords:
artesunate
- MeSH:
Methods;
artesunate;
Pharmaceutical Preparations
- From:Pharmaceutical Journal
1999;282(10):18-20
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Two current methods for assay of artesunate in our country have been validated and they meet the criteria for accuracy and precision; but do not meet criterion for specificity. Impurities in artesunate interfere with determinations. Result of artesunate determination according to quality specifications in-house increased 5.6% when 1% of succinic acid was presented in the sample to be assayed. If artesunate was assayed according to official quality specifications, result of the determination increased 1.4% when 1% of DHA is presented in the sample to be determined.
