Profile and Correlates of Health-related Quality of Life in Chinese Patients with Coronary Heart Disease.
- Author:
Ling WANG
;
Yi-Qun WU
;
Xun TANG
;
Na LI
;
Liu HE
;
Yang CAO
;
Da-Fang CHEN
;
Yong-Hua HU
1
Author Information
- Publication Type:Journal Article
- MeSH: Aged; Aged, 80 and over; China; epidemiology; Coronary Disease; epidemiology; Cross-Sectional Studies; Female; Humans; Linear Models; Male; Middle Aged; Quality of Life; Risk Factors; Socioeconomic Factors
- From: Chinese Medical Journal 2015;128(14):1853-1861
- CountryChina
- Language:English
-
Abstract:
BACKGROUNDAlthough coronary heart disease (CHD) is one of the major cardiovascular diseases, risk factors associated with the health-related quality of life (HRQoL) of CHD patients remain unclear. The present study was designed to determine the profile and significant factors of the HRQoL in CHD patients.
METHODSA cross-sectional study was conducted in rural communities of Fangshan District, Beijing, China. Socio-demographic, lifestyle, and comorbidity information of CHD patients were collected by a structured questionnaire and medical records. HRQoL was measured using European Quality of Life 5-dimensions (EQ-5D) scale and EQ Visual Analog Scale (EQ-VAS). Multiple linear and logistic regressions were performed to explore the association of potential risk factors with HRQoL scores and each EQ-5D, respectively.
RESULTSTotally, 1928 CHD patients (mean age 61.64 ± 9.24 years; female:male = 2.4:1) were enrolled in the study. The mean score of EQ-5D index and EQ-VAS were 0.889 ± 0.172 and 71.56 ± 17.65, respectively. Multiple linear regression revealed that marital status, physical activity, moderate alcohol drinking, and family's population were positive independent correlates of EQ-VAS, whereas diabetes mellitus and stroke were negative independent correlates (all P < 0.05). Age and stroke were negatively while physical activity, moderate alcohol drinking, family's population and household income were positively correlated with EQ-5D index (all P < 0.05) independently. In addition, each of the five HRQoL dimensions had various specific determinants, including obesity, underweight, smoking or education.
CONCLUSIONSFindings of the study highlight certain socio-demographic, lifestyle factors, and comorbid stroke or diabetes mellitus as correlates of HRQoL in Chinese CHD patients. Large-scale cohort studies should be carried out to confirm our results in the future.