High Killips Class as a Predictor of New-onset Atrial Fibrillation Following Acute Myocardial Infarction: Systematic Review and Meta-analysis.
- Author:
En-Yuan ZHANG
;
Li CUI
;
Zhen-Yu LI
;
Tong LIU
;
Guang-Ping LI
1
Author Information
- Publication Type:Journal Article
- MeSH: Atrial Fibrillation; diagnosis; etiology; Humans; Myocardial Infarction; complications; Risk Factors
- From: Chinese Medical Journal 2015;128(14):1964-1968
- CountryChina
- Language:English
-
Abstract:
BACKGROUNDRecent observational studies have shown that patients with higher Killips score (>I) have higher risk of new-onset atrial fibrillation (NOAF) following acute myocardial infarction (AMI), while others drew a neutral conclusion. The ultimate predictive value of high Killips class on NOAF remained obscure.
METHODSPubMed, Web of Science, China National Knowledge Infrastructure, and the Cochrane Controlled Trials Register Databases were searched until February 2015. Of the 3732 initially identified studies, 5 observational studies with 10,053 patients were analyzed.
RESULTSThe meta-analysis of these studies showed that higher Killips score on admission was associated with higher incidence of NOAF following AMI (odds ratio = 2.29, 95% confidence interval 1.96-2.67, P < 0.00001), while no significant differences exist among individual trials (P = 0.14 and I2 = 43%).
CONCLUSIONSKillips class >I was associated with the higher opportunity of developing NOAF following AMI.
