Outcomes and correlated factors in patients with impaired fasting glucose: a ten-year follow-up analysis.

Jingwen Zhou; Jiahui WU; Zhu Liang; Siqin Tong; Weijun Tong; Yonghong Zhang; Shaoyan Zhang

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Outcomes and correlated factors in patients with impaired fasting glucose: a ten-year follow-up analysis.

Author: Jingwen ZHOU ¹ ; Jiahui WU ¹ ; Zhu LIANG ¹ ; Siqin TONG ² ; Weijun TONG ¹ ; Yonghong ZHANG ¹ ; Shaoyan ZHANG ³
Author Information

1. Department of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou 215123, China.
2. Health Center of Guribanhua Township, Naiman, Tongliao, Inner Mongolia.
3. Department of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou 215123, China. Email: zhangsy@suda.edu.cn.
Publication Type:Journal Article
MeSH: Blood Glucose; analysis; China; epidemiology; Diabetes Mellitus, Type 2; epidemiology; Fasting; blood; Follow-Up Studies; Humans; Obesity; epidemiology; Prediabetic State; epidemiology; Risk Factors
From: Chinese Journal of Epidemiology 2014;35(11):1241-1243
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo investigate the outcomes and relative risk factors in subjects with impaired fasting glucose in Inner Mongolia, China.
METHODA total number of 32 villages in Kezuohou Banner and Naiman areas in Inner Mongolia were selected as the baseline surveys study fields from 2002 to 2003. Patients with IFG (5.6 mmol/L≤FPG<7.0 mmol/L) but without history of diabetes were selected as the study subjects. A follow-up study was conducted in 2013. Multinomial logistic regression analysis was used to evaluate the correlated factors.
RESULTSThere were 384 patients with IFG recruited in the study. Out of them, 150 (39.1%) progressed to normoglycaemia, 174 (45.3%) remained as IFG, and 60 (15.6%) developed into type 2 diabetes mellitus. Through adjustment multivariately, patients that returning to the status of normoglycaemia were significantly associated under the function of TG (OR = 0.692, 95%CI:0.502-0.952, P < 0.05)and those developed to diabetes were significantly associated with factors as age(OR = 1.052, 95%CI:1.014-1.090, P < 0.05) or obesity (OR = 2.924, 95% CI:1.353-6.320, P < 0.05).
CONCLUSION15.6% of the IFG patients developed diabetes mellitus among the Inner Mongolian population. Elevated TG was an inhibition factor for patients returning to normoglycaemia while both age and abdominal obesity were risk factors for the development of diabetes in the Inner Mongolian population.