Analysis of genetic polymorphisms of 15 STR loci among ethnic Hans from Xiamen.
- Author:
Lili WU
1
;
Peng RAN
;
Xiujuan ZHENG
;
Juanjuan ZHOU
;
Bin PEI
;
Xiuyu SONG
Author Information
- Publication Type:Journal Article
- MeSH: Alleles; Asian Continental Ancestry Group; genetics; Chi-Square Distribution; China; Forensic Genetics; methods; Gene Frequency; Genetics, Population; methods; Genotype; Humans; Linkage Disequilibrium; Microsatellite Repeats; genetics; Polymorphism, Genetic
- From: Chinese Journal of Medical Genetics 2017;34(1):115-117
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo assess the value of 15 short tandem repeat (STR) loci selected by an AmpFLSTR Identifilersystem for personal identification and paternity testing among ethnic Hans from Xiamen, Fujian.
METHODSFor 400 unrelated individuals, allelic frequencies for the 15 STR loci from the AmpFLSTR Identifilerkit were determined. Population genetics parameters for forensic usage were calculated.
RESULTSNo deviation of the observed allele frequency from Hardy-Weinberg equilibrium expectations was found by Chi-square test (P>0.05). All of the 15 loci were highly polymorphic. Observed heterozygosity has varied between 0.580 and 0.868. Matching probability was between 0.036 and 0.148. Power of discrimination was between 0.798 and 0.967. Polymorphic information content was between 0.560 and 0.850. And power of exclusion was between 0.268 and 0.730.
CONCLUSIONAll of the 15 loci selected by the AmpFLSTR Identifilersystem are highly polymorphic among ethnic Hans from Xiamen. By determining the alleles and allelic frequencies, data for genetic polymorphisms usable for paternity testing and personal identification for local population were obtained.
