Advance in the methods of preimplantation genetic diagnosis for single gene diseases.
10.3760/cma.j.issn.1003-9406.2017.03.030
- Author:
Yixin REN
1
,
2
,
3
;
Jie QIAO
;
Liying YAN
Author Information
1. Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Third Hospital, Peking University
2. Key Laboratory of Assisted Reproduction, Ministry of Education
3. Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology, Beijing 100191, China. yanliyingkind@aliyun.com.
- Publication Type:Journal Article
- MeSH:
Animals;
Female;
Fertilization in Vitro;
Genetic Diseases, Inborn;
diagnosis;
embryology;
genetics;
Humans;
Pregnancy;
Preimplantation Diagnosis;
methods;
trends;
Prenatal Diagnosis;
methods;
trends
- From:
Chinese Journal of Medical Genetics
2017;34(3):443-447
- CountryChina
- Language:Chinese
-
Abstract:
More than 7000 single gene diseases have been identified and most of them lack effective treatment. As an early form of prenatal diagnosis, preimplantation genetic diagnosis (PGD) is a combination of in vitro fertilization and genetic diagnosis. PGD has been applied in clinics for more than 20 years to avoid the transmission of genetic defects through analysis of embryos at early stages of development. In this paper, a review for the recent advances in PGD for single gene diseases is provided.
