Investigation on reaction of fixation of artesunate on receptor of polymer chitosan
- Author:
Yen Thi Hai Le
- Publication Type:Journal Article
- Keywords:
artesunate
- MeSH:
Artesunate;
chitosan;
Pharmaceutical Preparations;
Medicine, Traditional;
Plants, Medicinal
- From:Pharmaceutical Journal
1999;282(10):14-17
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Achito was synthesized by grafting artesunate on to chitosan polymeric carrier without catalyst. The influence of some factors on this reaction have been investigated, such as: artesunate/chitosan ratio, reactive duration, reactive temperature. The studied results showed that: achito with the best grafted artesunate content 74.49% mol has been performed at the follows conditions: artesunate/chitosan ratio: 1/1(mol/mol), reactive duration: 2 hours, reactive temperature: 80oC in vacuum
