- Author:
Farjana NIKKON
1
;
M Rowshanul HABIB
;
Zahangir Alam SAUD
;
M Rezaul KARIM
Author Information
- Publication Type:Journal Article
- Keywords: Culex quinquefasciatus Say; Larvae; Larvicidal effect; Mosquitocidal; Tagetes erecta Linn.; Toxicity
- MeSH: Animals; Culex; drug effects; Flowers; chemistry; Insecticides; pharmacology; Lethal Dose 50; Parasitic Sensitivity Tests; Plant Extracts; pharmacology; Tagetes; chemistry
- From:Asian Pacific Journal of Tropical Biomedicine 2011;1(3):186-188
- CountryChina
- Language:English
-
Abstract:
OBJECTIVETo investigate mosquitocidal effects of ethanolic extract of flowers of Tagetes erecta (T. erecta) and its chloroform and petroleum ether soluble fractions against the larvae of Culex quinquefasciatus (Cx. quinquefasciatus).
METHODSThe fresh flowers of T. erecta were extracted in cold with ethanol (5.0 L) and after concentration, the ethanol extract was fractionated with chloroform and petroleum ether to afford a brownish syrupy suspension of ethanol extract (50.0 g), petroleum ether soluble fraction (18.6 g) and chloroform soluble fraction (23.8 g). The larvicidal effect of ethanol extract and their solvent fractions were determined by the standard procedure of WHO against different instars of Cx. quinquefasciatus.
RESULTSAmong the tested samples the chloroform soluble fractions showed the highest toxicity and consequently, the lowest LC50 values (14.14 µg/mL, 17.06 µg/mL, 36.88 µg/mL and 75.48 µg/mL) for all the instars larvae of Cx. quinquefasciatus. The larvae showed comparative tolerance in the course of increasing age and time.
CONCLUSIONSIt can be concluded that the flowers of T. erecta are very effective natural larvicide and could be useful against Cx. quinquefasciatus.