In vivo toxicity study of Lantana camara.

Author: Badakhshan Mahdi POUR ¹ ; Sreenivasan SASIDHARAN
Author Information

1. Department of Biotechnology, Faculty of Applied Sciences, AIMST University, Jalan Bedong-Semeling, Batu 3 1/2, Bukit Air Nasi, Bedong 08100, Kedah, Malaysia.
Publication Type:Journal Article
Keywords: Artemia salina; Lantana camara; Toxicity
MeSH: Animals; Artemia; drug effects; Dose-Response Relationship, Drug; Lantana; chemistry; Lethal Dose 50; Plant Components, Aerial; chemistry; Plant Extracts; toxicity; Plant Roots; chemistry
From:Asian Pacific Journal of Tropical Biomedicine 2011;1(3):230-232
CountryChina
Language:English
Abstract:
OBJECTIVETo investigate the toxicity of methanol extract of various parts (Root, Stem, Leaf, Flower and Fruit) of Lantana camara (L. Camara) in Artemia salina.
METHODSThe methanol extracts of L. camara were tested for in vivo brine shrimp lethality assay.
RESULTSAll the tested extract exhibited very low toxicity on brine shrimp larva. The results showed that the root extract was the most toxic part of L. camara and may have potential as anticancer agent.
CONCLUSIONSMethanolic extract of L. camara is relatively safe on short-term exposure.