A case report of herpetic and candidal esophagitis in an immunocompetent adult.
10.1016/S2221-1691(11)60037-3
- Author:
Vishwanath SATHYANARAYANAN
1
;
Abdul RAZAK
;
M Mukhyprana PRABHU
;
Kavitha SARAVU
;
Pai C GANESH
;
Anuradha K RAO
Author Information
1. Department of Internal Medicine, Kasturba Medical College, Manipal, Manipal University, Karnataka, India.
- Publication Type:Case Reports
- MeSH:
Adult;
Antifungal Agents;
therapeutic use;
Antiviral Agents;
therapeutic use;
Candidiasis;
diagnosis;
drug therapy;
microbiology;
Esophagitis;
diagnosis;
drug therapy;
microbiology;
virology;
Esophagus;
microbiology;
pathology;
virology;
Female;
Herpes Simplex;
diagnosis;
drug therapy;
virology;
Humans;
Inclusion Bodies, Viral;
Spores, Fungal;
Treatment Outcome
- From:Asian Pacific Journal of Tropical Biomedicine
2011;1(3):251-252
- CountryChina
- Language:English
-
Abstract:
Reports of combined candidal and herpetic esophagitis in immunocompetent states are rare and sporadic. A 44-year-old previously healthy lady presented with a one week history of progressive dysphagia, odynophagia and fever. Esophagogastroduodenoscopy (EGD) showed extensive desquamation of the entire esophagus except for distal 4 cm. Histopathological examination revealed ulcerated and inflamed squamous epithelium with the margin of ulcer showing a few overhanging squamous cells with dense eosinophilic cytoplasm, multinucleated and faceted nuclei with glassy chromatin, and an occasional Cowdry type A intranuclear inclusion bodies. Few candidal spores were seen in the underlying stroma. Intravenous acyclovir, fluconazole and pantoprazole were initiated. Oral analgesics were given for pain relief. She was treated for a total of 14 days. She showed significant improvement and was tolerating oral intake after discharge. The patient was asymptomatic with no evidence of recurrence at a 2-month follow-up.
