The relationship between microalbuminuria and plasma high sensitivity C reactive protein.
- Author:
Jiang-tao YAN
1
;
Hui YE
;
Dao-wen WANG
Author Information
- Publication Type:Journal Article
- MeSH: Aged; Albuminuria; urine; Asian Continental Ancestry Group; C-Reactive Protein; analysis; Enzyme-Linked Immunosorbent Assay; Female; Humans; Inflammation; Male; Middle Aged
- From:Chinese Journal of Cardiology 2005;33(6):534-535
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the relationship between microalbuminuria (MA) and plasma high sensitivity C reactive protein (hsCRP).
METHODThe plasma hsCRP level and urine albumin level of 746 Chinese people were detected with ELISA and analyzed, respectively.
RESULTThe hsCRP level of MA group increased significantly compared with the control group (2.23 +/- 3.35 mg/L vs 1.68 +/- 2.58 mg/L, P < 0.05), the incidence of MA increased significantly when the plasma hsCRP level was beyond 0.77 mg/L (P < 0.05); logistic analysis showed that the occurrence of MA was associated with the plasma hsCRP level (OR = 1.153, P < 0.05).
CONCLUSIONIncreased plasma hsCRP was probably involved in the occurrence of MA, suggesting that inflammation may deteriorate endothelial dysfunction.
