Investigation of degree of retarded liberation of artesunate from achito.
- Author:
Yen Thi Hai Le
- Publication Type:Journal Article
- Keywords:
artesunate
- MeSH:
Artesunate;
Pharmaceutical Preparations
- From:Pharmaceutical Journal
1999;282(10):15-171
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Achito compound was prepared by the grft-copolymerization of artesunate and chitosan. The dynamic of Achito hydrolytis process into artesunate and chitosan has been studied. The obtained results showed that: the artesunate content has been quickly released from polymeric carrier in the first hour, then it was slowly liberated in the following 24 hours. At the 24th hour 99% artesunate was released from the Achito. After 48 hours 100% artesunate was released.
