Formation of porous biodegradable scaffolds for tissue engineering.
- Author:
Baoqing HAO
1
;
Guangfu YIN
;
Liming SHE
;
Xiaobo JIANG
;
Changqiong ZHENG
Author Information
1. Center of the Biomedical Engineering, Sichuan University, Chengdu 610041.
- Publication Type:Journal Article
- MeSH:
Absorbable Implants;
Biocompatible Materials;
Lactic Acid;
chemistry;
Polyesters;
Polyglycolic Acid;
chemistry;
Polymers;
chemistry;
Surface Properties;
Tissue Engineering
- From:
Journal of Biomedical Engineering
2002;19(1):140-171
- CountryChina
- Language:Chinese
-
Abstract:
This newly-emerging field uses tissue-specific cells in a three-dimensional organization, provided by a scaffolding material, to return functionality of the organ. For these applications, the choice of scaffolding material is crucial to the success of the technique. In addition to the chemical properties of the material, physical properties such as surface area for cell attachment are essential. Various methods of creating pores in these materials to increase surface area are reviewed here. Scaffolds formed using the different techniques, which include fiber bonding, solvent casting/particulate leaching, gas foaming and phase separation, are compared on the basis of porosity, pore size, and promotion of tissue growth.
