Methods for single unit recording in behavioring morphine craving rat.
- Author:
Su-Qing LIU
1
;
Jing WU
;
Jian-Zhen YANG
;
Shao-Hua TIAN
;
Nan-Hui CHEN
;
Yan-Lin LEI
;
Yan-Ping PENG
;
Jian-Hong WANG
;
Yuan-Ye MA
Author Information
1. Section of Primates Cognitive Brain Research, Kunming Institute of Zoology, the Chinese Academy of Sciences, Kunming 650223, China.
- Publication Type:Journal Article
- MeSH:
Action Potentials;
physiology;
Animals;
Electrophysiology;
instrumentation;
Hippocampus;
physiopathology;
Morphine Dependence;
physiopathology;
psychology;
Neurons;
physiology;
Rats;
Substance Withdrawal Syndrome;
physiopathology;
psychology
- From:
Acta Physiologica Sinica
2004;56(6):735-742
- CountryChina
- Language:Chinese
-
Abstract:
In this paper, one method was introduced, which was a combination of the cue-related morphine addiction model and a technique for obtaining chronic extracellular recordings of single unit in freely moving rats. With the combination and improvement of this technique, we have successfully applied this new method to study the neuronal activity of the hippocampus CA1 region in morphine withdrawal rats. In all, we found some more accurate and objective cellular characteristics of hippocampal neurons, and considered these characteristics as one of electrophysiological indexes of morphine addiction rats.
