Auto-hematopoietic stem cell transplantation for multiple myeloma accompanied with amyloidosis in four limbs.
- Author:
Hui-Hui SONG
1
;
Bao-An CHEN
;
Jia-Hua DING
;
Chong GAO
;
Yu-Qin TAO
;
Jing WANG
;
Jun WANG
;
Gang ZHAO
;
Yun-Yu SUN
;
Jian CHENG
;
Wen BAO
Author Information
1. Department of Hemotology, Zhongda Hospital, Southeast University, Nanjing, Jiangsu Province, China.
- Publication Type:Case Reports
- MeSH:
Amyloidosis;
complications;
Hematopoietic Stem Cell Transplantation;
Humans;
Male;
Middle Aged;
Multiple Myeloma;
complications;
surgery;
Transplantation, Autologous
- From:
Journal of Experimental Hematology
2009;17(3):770-773
- CountryChina
- Language:Chinese
-
Abstract:
The study was aimed to investigate the effective therapeutic method for patients with multiple myeloma accompanied with amyloidosis. A 58-year-old patient diagnosed as multiple myeloma accompanied with amyloidosis in four limbs was enrolled in this study. The various clinical and laboratorial examinations were performed, including bone marrow smear, immunologic test, radiography and so on. Patient received chemotherapeutic drugs and then autologous hematopoietic stem cell transplantation (auto-HSCT). The result showed that hematopoietic reconstitution was achieved at 23 days after auto-HSCT. Immunofixation electrophoresis was normal. There was only 0.6% plasma cells in the bone marrow. In conclusion, the auto-HSCT may be an effective treatment for multiple myeloma accompanied with amyloidosis in four limbs.