The application of measuring arterial blood pressure to the startle conditioned reflex in chronic animal model.
- Author:
Chun-Xiao ZHANG
1
;
Wen-Jie ZHANG
;
Min HUANG
;
Shao WANG
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Arteries; physiology; Blood Pressure; Conditioning, Classical; physiology; Female; Male; Models, Animal; Rats; Rats, Wistar; Reflex, Startle; physiology
- From: Chinese Journal of Applied Physiology 2003;19(4):398-401
- CountryChina
- Language:Chinese
-
Abstract:
AIMTo inquire a new credible animal model in studies of startle conditioned reflex.
METHODSThrough the trials of combining a conditioned stimulus (a tone) with an unconditioned stimulus(a foot shock), the startle responses were established in animals by conditioned stimulus. Arterial blood pressure were measured before and after blocking basolateral and lateral amygdala with lidocaine.
RESULTSThe blood pressure was increased by the conditioned stimulus after four days training. When the basolateral amygdala was blocked by lidocaine, the blood pressure was not increased by the conditioned stimulus.
CONCLUSIONThe animal model used and verified in this experiment is a new credible chronic animal model in startle conditioned reflex by measuring arterial blood pressure.
