Application df/dt(max) index for determinations of skeletal contractility.
- Author:
Jin GUO
1
;
Zhen-Jun TIAN
;
Liang TANG
;
Jian LIU
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Female; Mice; Mice, Inbred BALB C; Muscle Contraction; physiology; Muscle, Skeletal; physiology; ultrastructure; Swimming; physiology
- From: Chinese Journal of Applied Physiology 2003;19(4):413-415
- CountryChina
- Language:Chinese
-
Abstract:
AIMTo analyze the most force rising ratio (+ dF/dt(max)) and the most force descending ratio (- dF/dt(max)) for more sensitive index of skeletal contractility.
METHODSMouse model of swimming training was used, most force (f(max)), + dF/dt(max) and - dF/ dt(max) of gastrocnemius contracting were measured and changes of gastrocnemius supermicro-structure was observed.
RESULTSMitochondria increased and myoneme was regular in general training load, gastrocnemius F(max) - dF/dt(max) significantly increased than in control (P < 0.05), + dF/dt(max) increased more significantly (P < 0.01). Mitochondria was rare and myoneme was unusual in overtraining load, gastrocnemius F(max), - dF/dt(max) reduced significantly than in control (P < 0.05), + dF/dt(max) reduced more significantly (P < 0.01).
CONCLUSION+ dF/dt(max) is better index than F(max) in judging skeletal contractility.
