Effects of continuous blood purification on extravascular lung water and respiratory function in patients with extrapulmonary acute respiratory distress syndrome.
- Author:
Zhibo LI
1
;
Deliang WEN
;
Weijiang LIU
;
Xuming XIONG
Author Information
- Publication Type:Journal Article
- MeSH: Capillary Permeability; Extravascular Lung Water; Hemofiltration; Humans; Lung; Monitoring, Physiologic; Respiration; Respiratory Distress Syndrome, Adult; Retrospective Studies
- From: Journal of Southern Medical University 2015;35(7):1047-1049
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo assess the effects of continuous blood purification (CBP) on extravascular lung water and respiratory function in patients with extrapulmonary acute respiratory distress syndrome (ARDSexp).
METHODSThe data of 31 patients with ARDSexp admitted in our department were retrospectively analyzed.Sixteen of the patients received CBP, and the other 15 patients did not (control group). The level of extravascular lung water index (EVLWI), pulmonary vascular permeability index (PVPI), and respiratory function were measured before and after CPB.
RESULTSThe mortality rate was significantly lower in CBP group than in the control group (12.5% vs 33.3%, P<0.05). The patients in CPB group showed markedly earlier and significantly greater improvements in EVLWI, PVPI, PaO2/FiO, and respiratory function than the control patients (P<0.05).
CONCLUSIONCBP can reduce EVLWI and PVPI, improve pulmonary compliance and oxygenation, and reduce mortality rate in patients with ARDSexp.
