The Effects of Intranasal Midazolam on Preanesthetic Sedation in Children.
10.4097/kjae.1997.33.4.627
- Author:
Young Ju KIM
;
Cheoel Oh KIM
;
Yoon Hee KIM
;
Soo Chang SON
- Publication Type:Randomized Controlled Trial ; Original Article
- Keywords:
Age factors, children;
Anesthesia, pediatric;
Anesthetic technique, intranasal;
Premedication, midazolam
- MeSH:
Child*;
Humans;
Midazolam*
- From:Korean Journal of Anesthesiology
1997;33(4):627-632
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUNDS: This study was performed to determine the onset time and dose of intranasal midazolam used for preanesthetic sedation in children. METHODS: The children were randomly allocated to recieve one of three medications via the nasal route in a double blind manner. Group I: patients were given normal saline 0.2 ml/5kg, Group II: patients were given midazolam 0.2 mg/kg, Group III: patients were given midazolam 0.3 mg/kg. RESULTS: The cardiovascular and SpO2 changes were not significantly different among the patients of the three groups. The sedation score was greater in group II compared with group I from 5 minute after administration (1.9 vs 2.7, p<0.05). postanesthetic recovery score (PARS) was not significantly different among the three groups. CONCLUSIONS: It is suggested that intranasal midazolam (0.2 mg/kg) produces anxiolysis and sedation in children with rapid onset.
