Study on semisynthesis and factors influencing on the process of preparation of artelinic and mete artelinic acids
- Author:
Thu Nguyen Hung Thai
- Publication Type:Journal Article
- Keywords:
artelinic
- MeSH:
Artelinic acid;
Pharmaceutical Preparations;
therapeutics;
malaria
- From:Pharmaceutical Journal
1999;282(10):12-14
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Some new antimalarial water soluble derivatives of artemisinin were prepared by etherification of dihydroartemisinin with appropriate aryl alcohols. They are artelinat and metaartelinat. Influence of catalists and solvent on the etherification and the antimalarial activity of them as well as artesunat were studied.