A Case of Cerebral Aneurysmal Subarachnoid Hemorrhage in Fabry's Disease.
10.3340/jkns.2013.53.3.187
- Author:
Youn Hyuk CHANG
1
;
Sung Kyun HWANG
Author Information
1. Department of Neurosurgery, College of Medicine, Ewha Womans University, Seoul, Korea. nshsg@ewha.ac.kr
- Publication Type:Case Report
- Keywords:
Fabry's diseas;
Subarachnoid hemorrhage;
Cerebral aneurysm
- MeSH:
Aneurysm;
Arteries;
Biopsy, Needle;
Fabry Disease;
Female;
Humans;
Intracranial Aneurysm;
Kidney;
Mucolipidoses;
Nephrosis;
Proteinuria;
Risk Factors;
Subarachnoid Hemorrhage
- From:Journal of Korean Neurosurgical Society
2013;53(3):187-189
- CountryRepublic of Korea
- Language:English
-
Abstract:
We report an unusual case of cerebral aneurysmal subarachnoid hemorrage (SAH) with Fabry's disease. A 42-year-old woman presented with aneurysmal SAH originated from a saccular aneurysm of the right posterior communicating artery. The patient was treated by an endovascular coil embolization of aneurysm. Postoperatively the patient recovered favorably without any neurological deficit. During her admission, the patient had a sign of proteinuria in urine analysis. The pathologic findings of kidney needle biopsy implied nephrosialidosis (mucolipidosis of lysosomal stroage disease), which is consistent with a Fabry's disease. It is uncommon that Fabry's disease is presented with aneurysmal SAH, especially in middle-aged patients, but could be a clinical concern. Further investigations are needed to reveal risk factors, vascular anatomy, and causative mechanisms of Fabry's disease with aneurysmal SAH.
