Comparison of antimicrobial efficacy of four endodontic irrigants using an in vitro model infected by Enterococcus faecalis.
- Author:
Dong-mei WANG
1
;
Xue-jun GAO
;
Song SHEN
Author Information
- Publication Type:Journal Article
- MeSH: Chloramines; pharmacology; Chlorhexidine; pharmacology; Dental Pulp Cavity; microbiology; Enterococcus faecalis; drug effects; Humans; Hydrogen Peroxide; pharmacology; In Vitro Techniques; Root Canal Irrigants; pharmacology; Sodium Hypochlorite; pharmacology; Tosyl Compounds; pharmacology
- From: Chinese Journal of Stomatology 2007;42(4):223-224
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo compare the antimicrobial efficacy of four endodontic irrigants using an in vitro model infected by Enterococcus faecalis (Ef).
METHODSThe root canals of fifty extracted teeth were infected by Ef in vitro. The test groups were irrigated with 3% H(2)O(2), 2.5% sodium hypochlorite (SH), 2% chloramine-T (CR), and 2% chlorhexidine (CHX), respectively, and the control group was irrigated with 0.9% NaCl. The concentration of Ef in canals of each group was calculated before and after irrigation. The residual bacteria within the dentinal tubules and vitalities of the residual bacteria were also examined.
RESULTSAll chemical irrigants were significantly more effective than 0.9% NaCl (P < 0.05); 2.5% SH and 2% CHX were statistically more effective than 3% H(2)O(2) (P < 0.05). Residual bacteria could be found in the dentinal tubules and propagated 72 h after.
CONCLUSIONS2% CR and 2% CHX had almost the equivalent antimicrobial effect as 2.5% SH, but 3% H(2)O(2) was less effective.
