Sixty years after Hsiang-Tung Chang's presentation on dendrite at the Cold Spring Harbor Symposium.
- Author:
Yi-Zhang CHEN
1
Author Information
1. The Neuroscience Research Institute, Second Military Medical University, Shanghai, China. yzchen0928@yahoo.com
- Publication Type:Journal Article
- MeSH:
Calcium Signaling;
Dendrites;
physiology;
Glutamic Acid;
metabolism
- From:
Acta Physiologica Sinica
2012;64(5):499-503
- CountryChina
- Language:Chinese
-
Abstract:
Sixty years elapsed since Chang (Hsiang-Tung Chang, Xiang-Tong Zhang) presented his seminal report "Cortical neurons with particular reference to the apical dendrite" at the Cold Spring Harbor Symposium. Thanks to the development of elaborated techniques through the 6 decades, our understanding of the dendrite has been pushed forward greatly: the backward and forward conductions during excitation, sodium and calcium conductances, chemical excitation by uncaging glutamate at a dimension of micrometer, and the quantitative study of chemical organization of postsynaptic density (PSD), etc. Though the progression is great, there are still tough problems in dendritic research, especially the integration through dendritic spine.
