Differential clinical diagnostic parameters of acute hepatitis B and flare of chronic HBV infection.
- Author:
Hong ZHAO
1
;
Geng-shan TIAN
Author Information
- Publication Type:Journal Article
- MeSH: Acute Disease; Adult; Alanine Transaminase; blood; DNA, Viral; blood; Diagnosis, Differential; Hepatitis B; blood; diagnosis; immunology; Hepatitis B Antibodies; blood; Hepatitis B Surface Antigens; blood; Hepatitis B e Antigens; blood; Hepatitis B, Chronic; blood; diagnosis; immunology; Humans; Liver Function Tests; Middle Aged
- From: Chinese Journal of Experimental and Clinical Virology 2004;18(4):363-365
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate useful clinical diagnostic parameters for differentiating acute hepatitis B and flare of chronic HBV infection.
METHODSUsing PCR method to detect viral level in the patient's serum, HBV marker was detected by ELISA kit. Liver function was also detected.
RESULTSThe patient can be diagnosed as acute hepatitis B if a patient has one of the following parameters: (1)HBV-DNA negative on admission. (2) When the patient's ALT was lower than 400 IU/L, HBV-DNA was negative or HBsAg became negative or HBeAg/HBeAb seroconverted.
CONCLUSIONThe viral DNA level, HBV marker and ALT can help differentiate acute hepatitis B and flare of chronic HBV infection.
