Angiomyofibroblastoma of the Vulva: A case report.
- Author:
Mee Sook ROH
;
Hea Kyoung HUR
;
Sook Hee HONG
;
Sang Kap KIM
;
Young Cheol BAEK
;
Hwa Sook MOON
- Publication Type:Case Report
- Keywords:
Angiomyofibroblastoma;
Aggressive angiomyxoma;
Vulva
- MeSH:
Female;
Humans
- From:Korean Journal of Pathology
1996;30(4):344-346
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Angiomyofibroblastoma is a distinctive, hitherto uncharacterized, benign soft tissue tumor of the vulva with histology similar to an aggressive pelvic angiomyxoma. It can be distinguished from an aggressive angiomyxoma by its circumscribed borders, higher cellularity, more numerous blood vessels, the frequent presence of plump stromal cells, minimal stromal mucin, and rarity of erythrocyte extravasation. We experienced a case of angiomyofibroblastoma of the vulva occurring in a 45-year-old woman. The lesion was a well-defined but not encapsulated mass, 4.5x4.2 cm. Histologically the mass was characterized by alternating hypercellular and hypocellular edematous zones in which abundant blood vessels were irregularly distributed. Immunohistochemically, the spindled, plump spindled, and oval stromal cells were reactive for vimentin and desmin, but not for cytokeratin, or S-100 protein.
