Diagnostic Value of CD64Index of Neutrophils for Patients with Leukemia Combined with Early Infection.

Jian Guo; Jun Jia; Wen-zhong Che; Wen Yuan; Li-rui Kong

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Diagnostic Value of CD64Index of Neutrophils for Patients with Leukemia Combined with Early Infection.

Author: Jian GUO ¹ ; Jun JIA ² ; Wen-Zhong CHE ³ ; Wen YUAN ⁴ ; Li-Rui KONG ⁵
Author Information

1. Department of Clinical Laboratorial Examination, The Third People's Hospital of Qinghai Province, Xining 810007, Qinghai Province, China. E-mail: guojianqh07@163.com.
2. Department of Clinical Laboratorial Examination, Qinghai provincial Red Cross Hospital, Xining 810000, Qinghai Province, China.
3. Department of Clinical Laboratory Examination, Qinghai Provincial Hospital of Traditional Chinese Medicine, Xining 810000, Qinghai Province, China.
4. Department of Clinical Laboratorial Examination, Qinghai People's Hospital, Xining 810000, Qinghai Province, China.
5. Department of Clinical Laboratorial Examination, Pixian Traditional Chinese Medicine Hospital, Pixian 611730, Sichuan Province, China.
Publication Type:Journal Article
From: Journal of Experimental Hematology 2016;24(5):1375-1378
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo analyze the diagnostic value of CD64index of neutrophils for patients with leukemia combined with early infection.
METHODSFrom June 2014 to June 2015, 100 AL patients admitted in Third People's Hospital of Qinghai province were chosen as AL group, among them 50 AL patients were in infection group and other 50 patients were in non-infection group; at the same time, 200 healthy people were chosen as control group. The sensitivity, specificity and Youden's index of PCT, CRP, Neu% and CD64index in 300 subjects were calculated, and the diagnostic value of different indicators were compared.
RESULTSIn 100 AL patients, the sensitivitys of CD64, Neu%, PCT and CRP were respectively 88.00%, 82.00%, 74.00% and 70.00%; their spesitivitys were respectively 80.00%, 78.00%, 82.00% and 84.00%; their Youden's indexex of were respectively 0.68, 0.60, 0.56 and 0.54.
CONCLUSIONCD64index of neutrophils has diagnostic value for patients with leukemia combined with early infection.