- Author:
Shan-Hai OU
1
;
Jin-Zhen XIE
1
;
Ya-Li ZHANG
1
;
Hong-Ying NI
1
;
Xiu-Yu SONG
2
Author Information
- Publication Type:Journal Article
- From: Journal of Experimental Hematology 2016;24(5):1572-1576
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo estimate the prevalence of parvovirus B19 infection in Chinese Xiamen area blood donors.
METHODSBlood samples from blood donors were tested for detection of parvovirus B19 DNA and antibody. The direct sequencing and genetype analysis of B19 DNA positive samples were performed.
RESULTSSix out of 10452 samples were B19 DNA positive. The viral loads of the 6 samples were between 3.59×10-1.07×10IU/ml; the positive rate of B19-IgM was 4.64%(50/1078) and B19-IgG was 16.79%(181/1078). The positive rate of B19-IgG increased with ages, and was not related with the sex.
CONCLUSIONThe overall prevalence of parvovirus B19 infection in blood donors is lower in Chinese Xiamen area than that in other areas, however, there is still a certain percentage of viremia in donors and the attention should be paid to blood safety in the future work.