Value of deep small-bowel endoscopy in the diagnosis of Crohn's disease.
- Author:
Shao-Heng ZHANG
1
;
Jun XU
;
Qing QING
;
Fa-Chao ZHI
;
Yang BAI
;
Zhi-Min XU
;
Bo JIANG
;
Ya-Li ZHANG
;
Ye CHEN
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Capsule Endoscopy; Crohn Disease; diagnosis; pathology; Double-Balloon Enteroscopy; Female; Humans; Intestine, Small; pathology; Male; Retrospective Studies; Young Adult
- From: Journal of Southern Medical University 2011;31(4):637-640
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the value of deep small-bowel endoscopy (DSBE) in the diagnosis of Crohns disease (CD).
METHODSThe endoscopic and clinical data of 54 patients with CD receiving capsule endoscopy (CE) and double-balloon enteroscopy (DBE) between January, 2004 and December, 2008 were summarized and analyzed retrospectively.
RESULTSThe main indications for DSBE in our series were suspected CD (42.6%) and obscure gastrointestinal bleeding (25.9%). DSBE was obviously superior to barium imaging. The detection rate of CD was significantly higher with DSBE (92.6%) than with ileocolonoscopy (75.9%, P=0.017), and DSBE provides much more detailed descriptions of specific endoscopic features such as segmental distribution and lumen changes. DSBE significantly improve the diagnostic efficiency, giving priority to offer a guide and raise suspected diagnosis for CD.
CONCLUSIONDSBE is a valuable modality for detecting CD lesions in the jejunum and ileum and for evaluating lesion involvement and severity. The combination with a comprehensive analysis of routine imaging findings, gastro endoscopy, and clinical data can further enhance the diagnostic efficiency of DSBE.
