Pathogenic diagnosis of an unexplained epidemic event of infectious diarrhea.
- Author:
Yun-zhi LIU
1
;
Yi-wei HUANG
;
Miao JIN
;
Hong ZHANG
;
Fu-qiang LIU
;
Jing WANG
;
Shi-xiong HU
;
Xin-hua OU
;
Zhao-jun DUAN
Author Information
- Publication Type:Journal Article
- MeSH: Disease Outbreaks; Dysentery; diagnosis; epidemiology; genetics; Feces; virology; Gastroenteritis; epidemiology; virology; Humans; Molecular Epidemiology; Norovirus; classification; genetics; isolation & purification; Phylogeny; RNA, Viral; analysis; Reverse Transcriptase Polymerase Chain Reaction
- From: Chinese Journal of Experimental and Clinical Virology 2008;22(6):461-463
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo determine the pathogen of an unexplained epidemic event of infectious diarrhea by laboratory diagnosis of suspected cases samples.
METHODS28 samples from 28 suspected cases (22 fecal samples, 3 vomitus samples, 3 anus swab samples) were tested for Norovirus by RT-PCR. Sequencing and phylogenetic analysis were acomplished of 5 positive samples.
RESULTS160 of 5694 population were ill with an attack rate of 2.81%. The peak period was 7-9, March. 14 of 28 samples were tested Norovirus positive.Sequencing and phylogenetic analysis showed Norovirus type GII/4 was the causative agent and it had highest identity (97. 9%) with epidemic strain 2006b.
CONCLUSIONThe epidemic event ofinfectious diarrhea were caused by GII/4 Norovirus strains.
