Pathogenic diagnosis of an unexplained epidemic event of infectious diarrhea

VernacularTitle:一起不明原因感染性腹泻疫情的病原学诊断
Author: Yun-Zhi LIU ¹ ; Yi-Wei HUANG ; Miao JIN ; Hong ZHANG ; Fu-Qiang LIU ; Jing WANG ; Shi-Xiong HU ; Xin-Hua OU ; Zhao-Jun DUAN
Author Information

1. 湖南省疾病预防控制中心
Keywords: Norovims; Infextious diarrhea; Pathogenic
From: Chinese Journal of Experimental and Clinical Virology 2008;22(6):461-463
CountryChina
Language:Chinese
Abstract: Objective To determine the pathogen of an unexplained epidemic event of infectious diarrhea by laboratory diagnosis of suspected cases samples. Methods 28 samples from 28 suspected cases (22 fecal sarnples,3 vomitus samples,3 anus swab samples) were tested for Norovirus by RT-PCR. Sequencing and phylogenetic analysis were acomp|ished of 5 positive samples. Results 160 of 5694 population were ill with an attack rate of 2.81%. The peak period was 7-9,March. 14 of 28 samples were tested Norovirus positive. Sequencing and phylogenetic analysis showed Noruvirus type G Ⅱ/4 was the causative agent and it had highest identity (97.9% ) with epidemic strain 2006b. Conclusion The epidemic event of infectious diarrhea were caused by G Ⅱ/4 Norovirus strains.