Clinic value of combination of high-risk human papillomavirus test and cervical cytology test in diagnosing cervical lesions
10.3760/cma.j.issn.1003-9279.2008.06.026
- VernacularTitle:高危型人乳头状瘤病毒和宫颈细胞学联合检测在诊断宫颈病变中的临床价值
- Author:
Jin-Nian ZHOU
1
;
Jian ZHAO
;
Ying-Jie YANG
;
Qin-Ping LIAO
Author Information
1. 贵阳医学院附属医院
- Keywords:
Papillomavirus,human;
Cervix uteri,cytology;
Cervical diseases;
Diagnosis
- From:
Chinese Journal of Experimental and Clinical Virology
2008;22(6):478-480
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinic value of combination of high-risk human papillomavirus test and cervical cytology test in diagnosis of cervical lesions. Methods Patients underwent physical examination at our department were checked by high-risk human papillomavirus test,cervical cytology test and colposcope from October 2004 to December 2006. Abnormal patients with cervical abnormalities were asked for pathological test. The diagnostic value of cervical lesions among these different methods were compared. Results Based on the criteria of histopathology,the sensitivity,specificity,positive-predictive value and negative-predictive value of high-risk human papillomavirus test for detecting all cases of CIN Ⅱ and CIN Ⅲ were 94.83% ,31.06% ,55.22% and 87.02% respectively,and those of the cervical cytology were 92.10% ,31.06% ,54.50% and 81.43% respectively.Those values changed to 99.65%,18.55%,61.46% and 97.62% respectively if two methods were combined. Conclusions Human papillomavims test and cervical cytology test combined with pathological test can improve the detective rate of cervical lesions and facilitate the treatment.
