Relationship between psychological distress and T lymphocyte in HIV/AIDS patients
10.3760/cma.j.issn.1003-9279.2009.01.009
- VernacularTitle:HIV/AIDS患者负性情绪及其与外周血T细胞计数关系的探讨
- Author:
Si-Han LU
1
;
Xiao-Ping TANG
;
Xi-Long DENG
;
Wei-Lie CHEN
;
Rong-Xin HU
Author Information
1. 广东省广州市第八人民医院
- Keywords:
Acquired immunodeficiency syndrome;
T-lymphocyte subsetss;
Psychological tests
- From:
Chinese Journal of Experimental and Clinical Virology
2009;23(1):23-25
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between psychological distress and T lymphocyte counts in HIV/AIDS patients. Methods A total of 102 HIV/AIDS patients were raeasured by symptom check list(SCL-90), self-rating depressive scale (SDS) and sclf-rating anxiety scale(SAS). Patients were divided into 2 groups based on CD4+ T lymphocyte counts < 0.2×109/L (group A) and ≥0.2×109/L(group B).Results 77cases (75.49%) had psychological problems, including depression, relationship problems, psychosis, force etc. The prevalence of depression and anxiety were 67.65 % (69/102)and 43.13 % (44/102)respectively. The symptom of depression and anxiety of patients in group A were severer than those in group B ( P < 0.05 ). The CD4+ T lymphocyte counts were significantly negatively correlated with the total score, depression score, paranoid score and psychosis score of SCL-90 (all P < 0.05 ). Conclusion Most of the HIV/AIDS patients were in an obviously abnormal psychological status. The psychological distress symptom of HIV/AIDS patients might had negative effects on the number of CD4+ T lymphocyte.
