Human papillomavirus detection in clear cell carcinoma of the cervix.
- Author:
Yi-fan GUO
1
;
Ai-jun LIU
;
Xiao-li WANG
;
Xiao-zhou WU
;
Lei SONG
;
Hong-tu LIU
Author Information
- Publication Type:Journal Article
- MeSH: Adenocarcinoma, Clear Cell; diagnosis; virology; Adult; Female; Genotype; Human papillomavirus 18; genetics; isolation & purification; Humans; Papillomavirus Infections; diagnosis; virology; Paraffin Embedding; Polymerase Chain Reaction; Sensitivity and Specificity; Uterine Cervical Neoplasms; diagnosis; virology
- From: Chinese Journal of Experimental and Clinical Virology 2009;23(2):82-84
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the infection of the high risk human papillomavirus (HPV) in the specimen of the clear cell carcinoma of the cervix.
METHODSWe extracted the nucleic acids in the formalin-fixed and paraffin-embedded specimens from a 37-year-old patient with clear cell carcinoma of the cervix and detected the HPV genotype with the nested PCR.
RESULTSWe identified HPV18, a high-risk genotype, in the specimens.
CONCLUSIONThe HPV detection with the nested PCR was available for identification of the HPV genotype(s) in the paraffin-embedded specimens of clear cell carcinoma of the cervix (CCCC) with a high accuracy and sensitivity.
