Human papillomavirus detection in clear cell carcinoma of the cervix

VernacularTitle:宫颈透明细胞癌中人乳头瘤病毒的检测
Author: Yi-Fan GUO ¹ ; Ai-Jun HU ; Xiao-Li WANG ; Xiao-Zhou WU ; Lei SONG ; Hong-Tu LIU
Author Information

1. 解放军总医院
Keywords: Cervix neoplasms; Adenocarcinoma; Papillomavims,human; Reverse transcriptase polymerase chain reaction
From: Chinese Journal of Experimental and Clinical Virology 2009;23(2):82-84
CountryChina
Language:Chinese
Abstract: Objective To investigate the infection of the high risk human papillomavirus(HPV)in the specimen of the clear cell carcinoma of the cervix.Methods We extracted the nucleic acids in the formalin-fixed and paraffin-embedded specimens from a 37.year-old patient with clear cell carcinoma of the cervix and detected the HPV genotype with the nested PCR.Results We identified HPV18.a high-risk genotype,in the specimens. Conclusion The HPV detection with the nested PCR wag available for identification of the HW genotype(s)in the paraffin-embedded specimens of clear cell carcinoma of the cervix(CCCC)with a high accuracy and sensitivity.