Seroepidemical study of Coxsackievirus A 16, in four provinces, China, 2005
10.3760/cma.j.issn.1003-9279.2009.02.009
- VernacularTitle:2005年四省、区的柯萨奇病毒A组16型血清流行病学研究
- Author:
Zhao-Hui YANG
1
;
Shuang-Li ZHU
;
Hui ZHU
;
Hong-Qiu AN
;
Nai-Ying MAO
;
Yi-Xin JI
;
Xue-Bin GUO
;
Shao-Fu YIN
;
Zong-Jiu ZHANG
;
Wen-Bo XU
Author Information
1. 兰州大学
- Keywords:
Enterovirus B,human;
Hand,foot and mouth disease;
Serocpidemiologic studies
- From:
Chinese Journal of Experimental and Clinical Virology
2009;23(2):103-105
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the situation of 1-5 years old children's antibody against Coxsackieviras A group 16 strain( CVA16 )in Guangdong, Heilongjiang, Yunnan Province and Xinjiang Uygur Autonomous Regions, China,2005, it can offer scientific evidences for preventing and controlling CVA16 causative hand-food and mouth disease. Methods Using microneutrilisation test, to study 503 serum samples randomly selected from sera collected in 2005.Resulte. Positive rate of anti-CVA16 antibody were 41.90%, 9.40%, 40.00% and 34.40% in Gnangdong, Heilongjiang, Yunnan and Xinjiang, respectively. Antibody titer was relative low( average, 1:6.1 ) and there was no statistical difference of geometry mean of antibody titer (GMT) among Guangdong, Heilongjiang, Yunnan ( F = 0.97,0.40, 1.06, respectively; P > 0.05 ), while there had statistical difference of GMT between Heilongjiang and other three regions ( F = 10.61, P < 0.00). Conclusions There had probably existed local epidemic in some regions of Gnangdong, Heilongjiang, Yunnan Province and Xinjiang Uygur Autonomous Regions, China, 2005 or even before, but the area and degree of transmission and epidemic had difference. Children aged from 1-5 years old were relatively susceptible population of CVA16 infection.
