The level of TNF-α secretion of PBMC in patients with chronic hepatitis C and Nonalcoholic fatty liver
10.3760/cma.j.issn.1003-9279.2009.02.111
- VernacularTitle:慢性丙型肝炎合并非酒精性脂肪肝患者PBMC中TNF-α的研究
- Author:
Yi DONG
1
;
Hongfei ZHANG
;
Shishu ZHU
;
Hao CHEN
;
Jing LI
;
Yun CHENG
Author Information
1. 解放军第302医院
- Keywords:
Hepatitis C,Chronic;
Fatty liver,nonalcoholic;
Tumor necrosis factor
- From:
Chinese Journal of Experimental and Clinical Virology
2009;23(2):109-111
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the roles of TNF-α secretion of PBMC in patients with chronic hepatitis C and Nonalcoholic fatty liver. Methods The level of TNF-α secretion of PBMC in patients with chronic hepatitis C and Nonalcoholic fatty liver was detected by ELISA after culturing for 72 hours in vitro, as well as patients with chronic hepatitis C and the normal control. Results (1) Compared with the normal control, the level of TNF-α in group with chronic hepatitis C and in group with chronic hepatitis C and Nonalcoholic fatty liver notably increased. (2) Compared with the group with chronic hepatitis C, the level of TNF-α in group with chronic hepatitis C and Nonalcoholic fatty liver also notably increased. Conclusion It suggested TNF-α takes important roles in the infection course of chronic hepatitis C with Nonalcoholic fatty liver.
