Factors influencing leukemic dendritic cell cultivation in vitro-- review.
- Author:
Lin GUI
1
;
Jing LI
;
Bao-An CHEN
Author Information
1. Department of Hematology, Southeast University Medical Cellege, Bengbu 233000, Anhui Province, China.
- Publication Type:Journal Article
- MeSH:
Cell Culture Techniques;
Cell Differentiation;
Dendritic Cells;
cytology;
Humans;
Immunotherapy;
Leukemia;
immunology;
therapy
- From:
Journal of Experimental Hematology
2010;18(6):1649-1653
- CountryChina
- Language:Chinese
-
Abstract:
Leukemic dendritic cells, compared to normal dendritic cells, have the similar surface molecules, but have poor antigen-presenting function. When inoculated in the human body, the dendritic cells can not produce enough immune response. Therefore, how to make dendritic cells mature and have its own function to play a better anti-leukemia immune response is the key problem in clinical treatment. And it is one of the hottest studies in the immunotherapy field. This review focuses the recent progress of research on the culture of dendritic cells in vitro, its influence factors and so on.
