Correlation of CT Findings and Pathologic Nuclear Grading in Renal Cell Carcinoma.
10.3348/jkrs.1995.33.6.949
- Author:
Jong Chul KIM
;
Bin Young JUNG
- Publication Type:Original Article
- MeSH:
Carcinoma, Renal Cell*;
Humans;
Retrospective Studies;
Tomography, X-Ray Computed
- From:Journal of the Korean Radiological Society
1995;33(6):949-955
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To correlate the CT findings of renal cell carcinomas with nuclear grading in histopathology. MATERIALS AND METHODS: Preoperative CT scans and pathologic nuclear grading of 60 surgically resected renal cell carcinomas in 55 patients were retrospectively and independently reviewed. RESULTS: As nuclear grade increased, renal cell carcinomas were more likely to be of higher stage(92% of nuclear grade III renal cell carcinomas was of stage Ill, all Grade IV tumors were of stage IIIb or higher) and greater size(84% of grade III tumors and 100% of grade IV tumors>5cm in size) at presentation, and appeared more heterogeneous(84% of grade III tumors and 88% of grade IV tumors showed moderate or severe heterogeneity) and less well marginated(84% of grade Ill tumors and 100% of grade IV tumors had irregular or imperceptible margins). CONCLUSION: Small well-marginated homogeneous renal cell carcinomas were either nuclear grade I or II, and were distinguishable from the more aggressive nuclear grade III or IV lesions, which generally displayed irregular margins and greater inhomogeneity.
