Application of real-time tissue elastography in diagnosis of breast cancer.
- Author:
Xiu-fang ZHANG
1
;
Xue-ming LIU
;
Xiao-feng BAO
;
Xian-jing PENG
;
Wen ZHANG
;
Jun XU
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Aged; Breast Neoplasms; diagnostic imaging; pathology; Computer Systems; Diagnosis, Differential; Elasticity; Female; Humans; Image Enhancement; instrumentation; Middle Aged; Sensitivity and Specificity; Ultrasonography, Mammary; instrumentation
- From: Journal of Zhejiang University. Medical sciences 2006;35(4):444-447
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the clinical value of real-time tissue elastography (RTE) in the diagnosis of breast cancer.
METHODSOne hundred and twenty patients with breast lumps (135 lesions) were examined with B-mode imaging, color Doppler flowing imaging (CDFI) and RTE. The elastogram was graded using 5-score evaluating method. The postoperative pathological diagnosis was used as gold standard, and the sensitivity, specificity and accuracy of RTE and two-dimensional ultrasonography combined with RTE in diagnosis of breast cancer were calculated.
RESULTWhen the score >4 was set for cut-off criteria of malignancy, the sensitivity, specificity and accuracy of RTE was 85.45%, 83.75% and 84.4%, respectively. While two-dimensional ultrasonography combined with RTE was used, the sensitivity, specificity and accuracy increased up to 100%, 95% and 97%, respectively.
CONCLUSIONRTE combined with two-dimensional ultrasonography can improve the validity in the diagnosis of malignant breast lesions.
