Clinical study on colonic transmission time and the effect of sini powder on it in functional constipation patients.
- Author:
Zhao-hui JIN
1
;
Jian-hua DUAN
;
Hong-chuan ZHAO
Author Information
- Publication Type:Clinical Trial
- MeSH: Adult; Body Mass Index; Colon; drug effects; physiopathology; Colon, Sigmoid; drug effects; physiopathology; Constipation; drug therapy; physiopathology; Drugs, Chinese Herbal; therapeutic use; Female; Gastrointestinal Transit; drug effects; Humans; Male; Middle Aged; Phytotherapy; Time Factors; Treatment Outcome
- From: Chinese Journal of Integrated Traditional and Western Medicine 2006;26(10):896-898
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the characteristic of colonic transmission in functional constipation (FC) and the effect of traditional Chinese medicine (TCM) Sini Powder (SP) on it.
METHODSThe colonic transmission time (CTT) of 36 patients with FC (the FC group) and 22 healthy subjects (control group) was measured through colonic transmission test, and CTT of entire colon and that of various subsections was calculated with Hinton method and Arhan method respectively. After then, the FC group was treated with SP for 7 days, and CTT was detected again after treatment.
RESULTSBefore treatment, body mass index (BMI) was higher, CTT of entire colon, left half colonic section, and sigmoid-rectal section were longer in the FC group than those in the control group (P < 0.05), no statistical difference in CTT of right half colon was found between the two groups (P > 0.05). After FC patients being treated with SP, their CTT of whole colon, left half colonic section and sigmoid-rectal section were significantly shortened (P < 0.05).
CONCLUSIONFC patients were characterized by increased BMI and CTT prolonged and unevenly distributed in subsections, especially in the left half colon, sigmoid and rectum; SP could shorten the CTT in FC patients.
